With a high-res screen like the N800's, I'd like to use portrait-mode web browsing even for this site. Of course, then they'd have to let it scale smaller than 80%... Seriously, why let me zoom in to 300% (Is there anyone who uses that?!) and only out to 80%?
Someone mentioned slashdot. Other sites following the same narrow-column-of-content scheme include:
The Washington Times
SteynOnline
... and many other news sites.
Engadget
The Corner on NRO
... and many other bloggish beasts.

and, rcadden, on ITOS2007, there was a setting for the touch pressure threshold for which keyboard. Just updating my N800 now, so I don't know about OS08 yet; look in the control panel. If it's still there, perhaps it will alleviate the thumpishness.