For me personally not that much but porting from Pyside to Pyotherside will require a lot of work anyway. Porting from Pyside to Pyqt5 is very easy as shown below: Pyside: https://github.com/xerxes2/panucci/b...lui/qmlmain.py Pyqt5: https://github.com/xerxes2/panucci/b...ui/qml2main.py As I said I'm not using much Qt stuff other than Quick but porting to Pyotherside will still, if even possible, require a lot of work. Pyqt maps 1:1 with the C++ API and is very easy to use if you already used Pyside before. And would you care to explain why Pyotherside would use less resources than Pyqt? They're both using the same Qt libs so give some proof or it didn't happen. :P Use Pyotherside if you want but for existing Pyside apps Pyqt is the much faster way to port. Pyqt is GPL3 though so your app must use that license too or you must purchase a commercial license. Edit: Just to clarify, porting from Pyside to Pyqt5 is basically namespace changes but porting to Pyotherside will require a complete rewrite of your gui and some more stuff. I've never used Pyotherside so someone correct me if I'm wrong.