That's the setup I've got; I use Gnuite's "Driving Directions" web page to give me a route to follow, I load the directions into Maemo Mapper (I copy the text into leafpad and then save it on my N800), tell it to download maps all along the route, and then I pack up and head off.

The Holux is a satisfactory unit, too. It is tiny and seems to get a good fix under most circumstances.

My only complaint is that flite sounds like the speech synthesis they had on the Commodore 64. It isn't the lovely voice you get on many of these pro systems.