Ergonomy and the appearance.. I think this two are linked to each other very strongly.
For example, Thinkpad. Thinkpads are the most ergonomically advanced laptops I ever used (and using today, I mean the older series like T60-W500).
Also, imho they looks fantastic, as they are pretty much perfect in ergonomy.

So, if a laptop, that are basically just two rectangle with a hinge can looks so badass when its perfect to use, it both can be achieved in haldheld form.

Btw, Pandora looks a bit nicer than Pyra, which is strange at least..

Still, I'd rather choose something in the form of the OQO 2 for example.. looks more usable and portable, but it lacks the gaming controls though.