Occasionally I get a somewhat similar issue on the N800... Happens when systemui dies unexpectedly; have you been messing with softpoweroff by any chance?

You say, Home and Switcher? To me, those are the same key... Are you using one of those to refer to the Menu key (center-of-3 in N800, below dpad on N810) or Escape (CCW curly arrow, top-of-3 in N800 and immediately below Home/Switcher on N810)?

If you're referring to what I'd call Home and Escape, then it seems like all buttons on the face and top of the unit don't work, which begins to seem like a broken-cable sort of problem.