Not really. Buttons 1 & 2 are the ones you use when holding the wiimote as a game pad. Buttons A and B are used when you hold the wiimote "normally", B is located under your index, like a gun trigger. The A button is still easily accessible with the thumb that controls the directional pad, easily imaginable for "special functions". One question though: Most games get around the number of buttons and their disposition by either simplifying the layout or adding additional features (pull controller up, shake, etc). Is this not good enough for SNES games?