For your build_myapp.py I'm not sure what all PyQt4 brings down... but I used specifically the modules I needed to make space.. so for example: python2.5-qt4-gui python2.5-qt4-webkit python2.5-qt4-core python2.5-qt4-network etc. ETA: This should save some space for users downloading your app since they only grab what they need.. not the whole PyQt4 bindings.