Another issue i've notice since the update:

After a rom has been loaded, return to the main menu and press the Menu bar and press the "Save" button. In the save dialog box the default save location in now "bin" and I am unable to change it.

As far as the bios issue that some people are having I dont know what else to say. All I did was create the bios folder inside of /home/user/.picodrive and I copied the 2 bios files that I have used for years with the sega emulator for my PC.

If it makes you feel any better there does seem to be some sound issues on sega cd games. Sometimes sounds works and sometimes it doesnt. I have a feeling this is more a bios issue than an emulator issue.