I upgraded when it became available, primarily for Skype and secondarily for SDHC-support out of the box.
I haven't had any problems whatsoever, I even restored my backup in the full. Everything is good.
However, as it turns out there seem to be a problem with the SDHC support (see other thread), so I'm holding back on new cards for now. So, what I gained was: Skype, even better battery (by a small amount), improved flash. What I lost: Nothing. If you don't need Skype, and youtube isn't important, then one might as well hold back though.