Call me crazy, but I would reeeeaaaally like an emulated n95(ish) on one of my destktops - alphanumeric keypad, two button press to unlock (is it me or would it not make more sense for the usb to be on the right/bottom and the unlock switch on the left/top? This way you could unlock the device with your thumb whilst holding it with the same hand)

Basically an emulated candybar phone, designed for one handed operation. The only downside i can see is that without having physical buttons they would need to be bigger in order to be useable.