Craigy, I have been playing around with Handbrake including trying your profile.

Using my test setup your profile created a final file size of 143,374 whereas my own 'optimum' settings produce a file of 80,420. I don't see any discernable difference in quality, if anything my result might even play a little smoother.

I am happy to post a zip of my profile if you are interested in trying it?

My aim is to encode dvd's in one step, 5.7Gb dvd is now a 607Mb mp4.

Also my Handbrake files will only play on Nokia Media Player, MPlayer doesn't like them. This is a far as I have got.