What attila77 has suggested is your best bet, particularly if it's either pure html/javascript/etc. or the back-end is hosted on a public website and your intended users will always have internet access.

If the back-end is not public (or meant to be run on the same computer as the javascript, etc. code), you can get away with just porting it to Python 2.5 and running a simple Python web server (NOTE: for security, make sure it can only be accessed locally and block non-localhost referers!) If that's the way you want to go, look up "simple python web server" in Google. You can also combine that with QtWebkit (not that I have any experience with it).