As for cpu use, petrelli's powertop figures look fine. I'd also be concerned about skype though, especially if you're using 3g or wifi without maximum powersaving.

The way 3g works causes a single packet of data to keep the radio active for many seconds. (operator dependent)


Also one issue I used to have was with the "Automatically switch to wifi when available" option, or something like that. It would sometimes cause wifi to eat huge amounts of power when outside wifi range and using 2g/3g..
if wlan0/wmaster0 appears in '/sbin/ifconfig' output when on 2g/3g, I'd try do 'ifconfig wlan0 down' to cut off wifi.