If you read back a bit in this thread and other app threads you'll find this is not an issue with modRana, but is a system level flaw. Something goes wrong in the graphics driver, which is triggered by apps that do a lot of drawing to the screen. The result is that the screen never comes back on, since it's kernel driver is in a loop. If you SSH into the device, and use top(1) you'll see [sgx_misr] taking 98% of the CPU. This also explains the battery drain, as your CPU is running at near 100%.

Typically it happens more often when GPS is on, though it can happen just out of the blue. There's a bug for this here, which you should vote for if you want this fixed. The bigger problem is that this is a kernel level driver, so you can't kill it, nor can you remove it from the kernel since it's not a module. The only solution is a reboot.

I'm working on a script to monitor/detect this and shutdown the system after some warning that something's wrong with the system (just in case you're on the phone when it happens).

Edit: The script is done, and posted here.