Thanks for your respond, but "save remote" couldn't make it work.
I save my remotes everytime I've modify them, such as moving the buttons, or changing command of the buttons.

The problem might be that the application isn't make the IR port to send any data out (no blinking from the IR port as seen by some of my cameras).
It would be glad if the problem will be solved, I love this app.
But it's annoying me that when I want to use, I need to reinstall it...