Welcome to the forum!

i think that you can specify your situation a bit more, OTA upgrading can be complex.

1) Application incompatibily: Are you sure that you have EVERYTHING uninstalled?
2) Rootfs full: try df -h in the console. you need more than 50mb free. have you checked it out?
3) Unknown errors: a rootfs reflash is safe. use it as your last resort, but without fear (after a backup, of course)

Keep asking, and have fun!